Alexandrea "Alex" Borstein (born February 15, 1973) is an American actress, singer, voice actress, writer and comedian. She is best known for her long-running role as Lois Griffin on the animated television series Family Guy, and as a cast member on the sketch comedy series MADtv.
A native of Highland Park, Illinois, Borstein is a graduate of San Francisco State University, where she studied rhetoric. She was trained in improvisational comedy at the ACME Comedy Theatre, near Hollywood, California, and was selected to join MADtv after being scouted by talent agents who noticed her work at the theatre. She was a writer and voice actor for several television shows, including Casper, Pinky and the Brain and Power Rangers: Zeo, before joining the cast of MADtv as a featured player, and later as a repertory player in 1997.
As an actress, she has made appearances in such films as The Lizzie McGuire Movie, Catwoman and Dinner for Schmucks.

The Bad Guys 2
The Police Commissioner (voice)
2025

Alex Borstein: Corsets & Clown Suits
Self
2023

Maraschino Ruby
Police Chief Misty Luggins (voice)
2022

The Bad Guys
Police Chief Misty Luggins (voice)
2022

Extinct
Mali (voice)
2021

Resident Alien
Carlyn · (1 episode)
2021

Awkwafina is Nora From Queens
Wilma (voice) · (1 episode)
2020

The Kelly Clarkson Show
(1 episode)
2019

Las que faltaban
Invitada · (1 episode)
2019

The Marvelous Mrs. Maisel
Susie Myerson · (43 episodes)
2017

Gilmore Girls: A Year in the Life
Drella · (1 episode)
2016

Gilmore Girls: A Year in the Life
Miss Celine · (1 episode)
2016
Man Rots from the Head
Gladys
2016

The Angry Birds Movie
Sophie Bird / Peggy Bird (voice)
2016

Bordertown
Janice Buckwald · (13 episodes)
2016

Bordertown
Becky Buckwald · (13 episodes)
2016

TV's Funniest Animated Stars: A Paley Center for Media Special
Self
2015

Love the Coopers
Angie Cooper
2015

Robot Chicken DC Comics Special III: Magical Friendship
Wonder Woman (voice)
2015

Life in Pieces
Linette · (1 episode)
2015

The Late Show with Stephen Colbert
Self · (1 episode)
2015

Delirium
Lois Griffin (archive footage) · (1 episode)
2014

A Million Ways to Die in the West
Millie
2014

Robot Chicken DC Comics Special II: Villains in Paradise
Wonder Woman (voice)
2014

Late Night with Seth Meyers
Self · (1 episode)
2014

Getting On
Dawn Forchette · (18 episodes)
2013

Masters of Sex
Loretta · (1 episode)
2013

Robot Chicken: DC Comics Special
Wonder Woman / Giganta / Woman (voice)
2012

ParaNorman
Mrs. Henscher (voice)
2012

Ted
John's Mom
2012

Bunk
(2 episodes)
2012

For Christ's Sake
Mrs. Marcus
2011

Workaholics
Colleen Walker · (1 episode)
2011

Shameless
Lou Deckner · (5 episodes)
2011

Family Guy Presents: It's a Trap!
Lois Griffin as Princess Leia / Sy Snootles / Asian Woman / ET Announcer / Hot Girl's Mother (voice)
2010

Dinner for Schmucks
Red Hair Woman (uncredited)
2010

Hot in Cleveland
Preshi · (1 episode)
2010

Killers
Mrs. Baily
2010

Family Guy Presents: Something, Something, Something, Dark Side
Lois Griffin as Princess Leia / OnStar Voiceover / Empire Member's Wife / Robot Wife (voice)
2009

Family Guy Presents: Seth & Alex's Almost Live Comedy Show
Self / Various (voice)
2009

The Cleveland Show
(8 episodes)
2009

Family Guy Presents: Stewie Kills Lois and Lois Kills Stewie
Lois Griffin (voice)
2009

Seth MacFarlane's Cavalcade of Cartoon Comedy
Various Characters (voice) · (50 episodes)
2008

Family Guy Presents: Blue Harvest
Lois Griffin as Princess Leia / Barbara Pewterschmidt as Aunt Beru (voice)
2008

The Lookout
Mrs. Lange
2007

The Thick Of It
Hope Mueller
2007
Drop Dead Gorgeous (In a Down-to-Earth Bombshell Sort of Way)
2006

Talkshow with Spike Feresten
(1 episode)
2006

Little Man
Janet
2006

Good Night, and Good Luck.
Natalie
2005
Too Late with Adam Carolla
(1 episode)
2005

Family Guy Presents: Stewie Griffin: The Untold Story
Lois Griffin / Various Characters (voice)
2005

Kicking & Screaming
Obnoxious Hummer Lady (uncredited)
2005

American Dad!
(1 episode)
2005

Billy's Dad Is a Fudge-Packer
Betty Henderson
2004

Drawn Together
Jelly Donuts Leader (voice) · (1 episode)
2004

Drawn Together
AIDS Walk Coordinator / Lois Griffin (voice) · (1 episode)
2004

Catwoman
Sally
2004
Celebrity Blackjack
(19 episodes)
2004

Seeing Other People
Tracy
2004

Bad Santa
Milwaukee Mom with Photo
2003

The Lizzie McGuire Movie
Miss Ungermeyer
2003

Jimmy Kimmel Live!
Self · (2 episodes)
2003

Showtime
Casting Director
2002
Never Mind the Buzzcocks
Self · (1 episode)
2002

Dawg
Darcy Smits
2002

A Very Special Family Guy Freakin' Christmas
Lois Griffin / Female Hipster / Julie / Grandma (voice)
2001

Gary & Mike
Maya (voice) · (1 episode)
2001

Gilmore Girls
Drella · (4 episodes)
2000

Gilmore Girls
Miss Celine · (2 episodes)
2000

Titus
(1 episode)
2000

Family Guy
Lois Griffin / Tricia Takanawa / Loretta Brown / Barbara Pewterschmidt (voice) · (442 episodes)
1999

Big Bad BeetleBorgs
Cataclaws (voice) · (1 episode)
1996

Power Rangers Zeo: Zeo Quest
Queen Machina (voice)
1996

MADtv
Various · (109 episodes)
1995

MADtv
Ms Swan / Karen · (1 episode)
1995

MADtv
Ms. Swan, Mama Brightling · (1 episode)
1995

Friends
Bitter Woman on Stage · (1 episode)
1994

Frasier
Evelyn · (1 episode)
1993

Power Rangers
Queen Machina (voice) · (50 episodes)
1993