Anthony Gonzalez

Miguel Rivera (voice)

Gael García Bernal

Héctor (voice)

Benjamin Bratt

Ernesto de la Cruz (voice)

Alanna Ubach

Mamá Imelda Rivera (voice)

Renee Victor

Elena Rivera (voice)

Ana Ofelia Murguía

Mamá Socorro "Coco" Rivera (voice)

Edward James Olmos

Chicharrón (voice)

Jaime Camil

Papá Enrique Rivera (voice)

Alfonso Arau

Papá Julio Rivera (voice)

Herbert Siguenza

Tío Oscar Rivera / Tío Felipe Rivera (voice)

Lombardo Boyar

Mariachi / Gustavo (voice)

Sofía Espinosa

Mamá Luisa Rivera (voice)

Dyana Ortelli

Tía Victoria Rivera (voice)

Gabriel Iglesias

Head Clerk (voice)

Selene Luna

Tía Rosita Rivera (voice)

Natalia Cordova-Buckley

Frida Kahlo (voice)

Carla Medina

Departure Agent (voice)

Luis Valdez

Tío Berto Rivera / Don Hidalgo (voice)

Blanca Araceli

Emcee (voice)

Polo Rojas

Abel Rivera (voice)

Montse Hernandez

Rosa Rivera (voice)

Octavio Solis

Arrival Agent (voice)

Cheech Marin

Corrections Officer (voice)

Salvador Reyes

Security Guard (voice)

John Ratzenberger

Juan Ortodoncia (voice)